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How do you feel about the future of presbyopia solutions? EYE AM READY

EYE AM
PRECISE

Current presbyopia treatments do not constrict the pupil to the ideal targeted size.1

EYE AM PRECISE

PUPIL SIZE
MATTERS

Future presbyopia solutions are focusing on iris sphincter constriction to drive depth-of-focus as a surrogate for accommodation.2

EYE AM PRECISE

PUPIL SIZE
MATTERS

Pupil size is an important consideration when selecting a treatment option for presbyopia.5

EYE AM PRECISE

PUPIL SIZE
MATTERS

Research shows appropriately reducing the pupil diameter dramatically increases depth-of-focus for presbyopes.6

EYE AM PRECISE

PUPIL SIZE
MATTERS

For presbyopes, a pinhole-sized pupil provides near vision improvement across a broad range of lighting conditions.7

EYE AM
TARGETED

Ideal presbyopia solutions aspire to reduce pupil size by predominantly targeting the iris sphincter muscle.2

EYE AM TARGETED

FOCUS ON THE IRIS SPHINCTER

Graphic of iris sphincter.
The lens hardens with age, limiting accommodation and impacting near vision3,4 The lens hardens with age, limiting accommodation and impacting near vision3,4 A pinhole pupil allows light that will focus on the retina as a surrogate for accommodation A pinhole pupil allows light that will focus on the retina as a surrogate for accommodation In presbyopia, selectively targeting the iris sphincter disassociates pupil size from myopic shift2 In presbyopia, selectively targeting the iris sphincter disassociates pupil size from myopic shift2
Chart showing increased depth-of-focus with reduced pupil diameter
Chart showing near vision improvement with reduced pupil diameter.

*Psychophysical visual acuity was tested using an 8 orientation, forced choice paradigm, using maximum contrast Landolt C targets, while independently controlling pupil size, defocus levels, and luminance. Pupil was manipulated with 8 artificial pupils (1, 1.3, 1.6, 2, 2.5, 3, 4, 6 mm) imaged onto the patient's dilated entrance; N=2.7

EYE AM SELECTIVE

128 MILLION

people in the US are impacted by presbyopia8

The majority of the 128 million would seriously consider a new presbyopia solution.

Who should you prioritize?

MAJORITY

would seriously consider a new solution9*

WHO ARE THEY?

Invested in glasses-free vision

May be dissatisfied with multifocal contacts

May drop wearing due to presbyopia10

*In a LENZ commissioned survey of 1358 presbyopes.
Monofocal lens wearers (n=110); multifocal lens wearers (n=22).
Percentage of those who seriously would consider (n=86).9

8 in 10
would seriously consider
a new solution9*
* In a LENZ commissioned survey of 1358 presbyopes.
Med spa clients who selected one beauty category (n=182).
Percentage of those who seriously would consider (n=142).9
WHO ARE THEY?
Have a "look good, feel good"
mindset
Have been to a med spa in the
last 12 months
Believe glasses impede their
seamless aesthetic
* In a LENZ commissioned survey of 1358 presbyopes.
Med spa clients who selected one beauty category (n=182).
Percentage of those who seriously would consider (n=142).9

APPROXIMATELY 75

%

would seriously consider
a new solution9*

WHO ARE THEY?

Previously had
refractive surgery

Report that
refractive surgery
has "worn off"

Invested in
glasses-free
vision

*In a LENZ commissioned survey of 1358 presbyopes.
Post-LASIK patients (n=112); post-PRK patients (n=19).
Percentage of those who seriously would consider (n=99).9

people icon
Contact lenses icon Contact Lenses icon
Med Spa Client icon Med Spa Client icon
LASIK surgery icon LASIK surgery icon

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SHAPE THE FUTURE OF PRESBYOPIA SOLUTIONS

Visit us at upcoming conventions and share your voice

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  • AAO

Hear what other eyecare professionals are saying about the future of presbyopia:

REFERENCES: 1. Charters L. Presbyopia: the ever-changing environment and elusive Holy Grail. Optometry Times. 2022;14(12). Accessed December 12, 2023. https://www.optometrytimes.com/view/presbyopia-the-ever-changing-environment-and-elusive-holy-grail 2. Eiden SB, Odrich M. Differentiating miotics for pharmacological management of presbyopia. Presbyopia Physician. 2023;3. https://www.presbyopiaphysician.com/issues/2023/september-2023/differentiating-miotics-for-pharmacological-manage 3. Presbyopia. National Eye Institute. Updated November 15, 2023. Accessed December 12, 2023. https://www.nei.nih.gov/learn-about-eye-health/eye-conditions-and-diseases/presbyopia 4. Han X, Ellwein LB, Guo X, et al. Progression of near vision loss and incidence of near vision impairment in an adult Chinese population. Ophthalmology. 2017;124(5):734-742. doi:10.1016/j.ophtha.2017.01.020 5. Coats J. Pupil size matters in presbyopia treatment. Optometry Times. 2021;13(9). Accessed December 12, 2023. https://www.optometrytimes.com/view/pupil-size-matters-in-presbyopia-treatment 6. Charman WN. Pinholes and presbyopia: solution or sideshow? Ophthalmic Physiol Opt. 2019;39:1-10. doi.org/10.1111/opo.12594 7. Xu R, Thibos L, Bradley A. Effect of target luminance on optimum pupil diameter for presbyopic eyes. Optim Vis Sci. 2016;93(11):1409-1419. doi:10.1097/OPX.0000000000000963 8. American Optometric Association. For 128 million U.S. presbyopes, doctors of optometry can provide treatment options. August 24, 2023. Accessed December 12, 2023. https://www.aoa.org/news/clinical-eye-care/diseases-and-conditions/for-128-million-us-presbyopes-doctors-of-optometry-can-provide-treatment-options?sso=y 9. Data on file. Lenz Therapeutics. 10. Cohen S, Whittam D. Tackling the problem of contact lens dropout from presbyopia. Optometry Times. 2022;14(3). Accessed December 12, 2023. https://www.optometrytimes.com/view/tackling-the-problem-of-contact-lens-dropout-from-presbyopia

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